Plenty options:
1. Manually edit opcodes (hex replace mode) possible by DEXExplorer http://forum.exetools.com/showthread.php?t=18117
2. URET Android Reverser Toolkit v1.2: Decompile and Compile APK: smali text code editing and recompile
3. org.jf.dexlib https://android.googlesource.com/toolchain/jack/+/ub-jack/dexlib
if you wanna edit apks programmatically
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